AGAP2-TMEM67 Fusion FISH Probe
The AGAP2-TMEM67 Fusion FISH Probe is used to confirm a fusion of the AGAP2 and TMEM67 genes. The fusion of the AGAP2 and TMEM67 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGAP2-TMEM67-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-RERE | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-REOR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-REGO | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-REGR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-REAQ | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-ORRE | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-OROR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-ORGO | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GORE | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GOOR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GOGO | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GOGR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GRRE | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GROR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GRGO | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GRGR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-AQRE | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-AQOR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-AQGO | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-AQGR | 20 (40 μL) | 200 μL |
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| AGAP2-TMEM67-20-AQAQ | 20 (40 μL) | 200 μL |
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TMEM67 Gene Summary
The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). [provided by RefSeq, Nov 2008]
Gene Name: Transmembrane Protein 67
Chromosome: CHR8: 94767071 -94831460
Locus: 8q22.1
AGAP2 Gene Summary
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2
Chromosome: CHR12: 58118075 -58135944
Locus: 12q14.1
Gene Diseases
The AGAP2 TMEM67 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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