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AGR2-ANXA1 Fusion FISH Probe

The AGR2-ANXA1 Fusion FISH Probe is used to confirm a fusion of the AGR2 and ANXA1 genes. The fusion of the AGR2 and ANXA1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AGR2-ANXA1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AGR2-ANXA1-20-RERE 20 (40 μL) 200 μL
AGR2-ANXA1-20-REOR 20 (40 μL) 200 μL
AGR2-ANXA1-20-REGO 20 (40 μL) 200 μL
AGR2-ANXA1-20-REGR 20 (40 μL) 200 μL
AGR2-ANXA1-20-REAQ 20 (40 μL) 200 μL
AGR2-ANXA1-20-ORRE 20 (40 μL) 200 μL
AGR2-ANXA1-20-OROR 20 (40 μL) 200 μL
AGR2-ANXA1-20-ORGO 20 (40 μL) 200 μL
AGR2-ANXA1-20-ORAQ 20 (40 μL) 200 μL
AGR2-ANXA1-20-GORE 20 (40 μL) 200 μL
AGR2-ANXA1-20-GOOR 20 (40 μL) 200 μL
AGR2-ANXA1-20-GOGO 20 (40 μL) 200 μL
AGR2-ANXA1-20-GOGR 20 (40 μL) 200 μL
AGR2-ANXA1-20-GOAQ 20 (40 μL) 200 μL
AGR2-ANXA1-20-GRRE 20 (40 μL) 200 μL
AGR2-ANXA1-20-GROR 20 (40 μL) 200 μL
AGR2-ANXA1-20-GRGO 20 (40 μL) 200 μL
AGR2-ANXA1-20-GRGR 20 (40 μL) 200 μL
AGR2-ANXA1-20-GRAQ 20 (40 μL) 200 μL
AGR2-ANXA1-20-AQRE 20 (40 μL) 200 μL
AGR2-ANXA1-20-AQOR 20 (40 μL) 200 μL
AGR2-ANXA1-20-AQGO 20 (40 μL) 200 μL
AGR2-ANXA1-20-AQGR 20 (40 μL) 200 μL
AGR2-ANXA1-20-AQAQ 20 (40 μL) 200 μL

ANXA1 Gene Summary

This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]

Gene Name: Annexin A1

Chromosome: CHR9: 75766780 -75785307

Locus: 9q21.13

AGR2 Gene Summary

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]

Gene Name: Anterior Gradient 2, Protein Disulphide Isomerase Family Member

Chromosome: CHR7: 16832263 -16844738

Locus: 7p21.1

Gene Diseases

The AGR2 ANXA1 Fusion has been associated with the following diseases:

Disease Name
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.