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AHNAK-DPF2 Fusion FISH Probe

The AHNAK-DPF2 Fusion FISH Probe is used to confirm a fusion of the AHNAK and DPF2 genes. The fusion of the AHNAK and DPF2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AHNAK-DPF2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AHNAK-DPF2-20-RERE 20 (40 μL) 200 μL
AHNAK-DPF2-20-REOR 20 (40 μL) 200 μL
AHNAK-DPF2-20-REGO 20 (40 μL) 200 μL
AHNAK-DPF2-20-REGR 20 (40 μL) 200 μL
AHNAK-DPF2-20-REAQ 20 (40 μL) 200 μL
AHNAK-DPF2-20-ORRE 20 (40 μL) 200 μL
AHNAK-DPF2-20-OROR 20 (40 μL) 200 μL
AHNAK-DPF2-20-ORGO 20 (40 μL) 200 μL
AHNAK-DPF2-20-ORAQ 20 (40 μL) 200 μL
AHNAK-DPF2-20-GORE 20 (40 μL) 200 μL
AHNAK-DPF2-20-GOOR 20 (40 μL) 200 μL
AHNAK-DPF2-20-GOGO 20 (40 μL) 200 μL
AHNAK-DPF2-20-GOGR 20 (40 μL) 200 μL
AHNAK-DPF2-20-GOAQ 20 (40 μL) 200 μL
AHNAK-DPF2-20-GRRE 20 (40 μL) 200 μL
AHNAK-DPF2-20-GROR 20 (40 μL) 200 μL
AHNAK-DPF2-20-GRGO 20 (40 μL) 200 μL
AHNAK-DPF2-20-GRGR 20 (40 μL) 200 μL
AHNAK-DPF2-20-GRAQ 20 (40 μL) 200 μL
AHNAK-DPF2-20-AQRE 20 (40 μL) 200 μL
AHNAK-DPF2-20-AQOR 20 (40 μL) 200 μL
AHNAK-DPF2-20-AQGO 20 (40 μL) 200 μL
AHNAK-DPF2-20-AQGR 20 (40 μL) 200 μL
AHNAK-DPF2-20-AQAQ 20 (40 μL) 200 μL

DPF2 Gene Summary

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]

Gene Name: Double PHD Fingers 2

Chromosome: CHR11: 65101224 -65120451

Locus: 11q13.1

AHNAK Gene Summary

The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]

Gene Name: AHNAK Nucleoprotein

Chromosome: CHR11: 62201015 -62314332

Locus: 11q12.3

Gene Diseases

The AHNAK DPF2 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.