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ANKIB1-LMTK2 Fusion FISH Probe

The ANKIB1-LMTK2 Fusion FISH Probe is used to confirm a fusion of the ANKIB1 and LMTK2 genes. The fusion of the ANKIB1 and LMTK2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ANKIB1-LMTK2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-RERE 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-REOR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-REGO 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-REGR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-REAQ 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-ORRE 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-OROR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-ORGO 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-ORAQ 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GORE 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GOOR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GOGO 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GOGR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GOAQ 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GRRE 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GROR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GRGO 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GRGR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-GRAQ 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-AQRE 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-AQOR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-AQGO 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-AQGR 20 (40 μL) 200 μL
ANKIB1-LMTK2-20-AQAQ 20 (40 μL) 200 μL

LMTK2 Gene Summary

The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009]

Gene Name: Lemur Tyrosine Kinase 2

Chromosome: CHR7: 97736196 -97838944

Locus: 7q21.3

ANKIB1 Gene Summary

The Ankyrin Repeat And IBR Domain Containing 1 (ANKIB1) gene is located on chr7 :91875547-92030698 at 7q21.2.

Gene Name: Ankyrin Repeat And IBR Domain Containing 1

Chromosome: CHR7: 91875547 -92030698

Locus: 7q21.2

Gene Diseases

The ANKIB1 LMTK2 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.