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ANKRD11-SPIRE2 Fusion FISH Probe

The ANKRD11-SPIRE2 Fusion FISH Probe is used to confirm a fusion of the ANKRD11 and SPIRE2 genes. The fusion of the ANKRD11 and SPIRE2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ANKRD11-SPIRE2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-RERE 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-REOR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-REGO 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-REGR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-REAQ 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-ORRE 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-OROR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-ORGO 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-ORAQ 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GORE 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GOOR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GOGO 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GOGR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GOAQ 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GRRE 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GROR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GRGO 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GRGR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-GRAQ 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-AQRE 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-AQOR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-AQGO 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-AQGR 20 (40 μL) 200 μL
ANKRD11-SPIRE2-20-AQAQ 20 (40 μL) 200 μL

ANKRD11 Gene Summary

This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]

Gene Name: Ankyrin Repeat Domain 11

Chromosome: CHR16: 89334034 -89556969

Locus: 16q24.3

SPIRE2 Gene Summary

The Spire Type Actin Nucleation Factor 2 (SPIRE2) gene is located on chr16 :89894906-89937727 at 16q24.3.

Gene Name: Spire Type Actin Nucleation Factor 2

Chromosome: CHR16: 89894906 -89937727

Locus: 16q24.3

Gene Diseases

The ANKRD11 SPIRE2 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.