ANKS1B-NDUFA12 Fusion FISH Probe
The ANKS1B-NDUFA12 Fusion FISH Probe is used to confirm a fusion of the ANKS1B and NDUFA12 genes. The fusion of the ANKS1B and NDUFA12 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKS1B-NDUFA12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-RERE | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-REOR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-REGO | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-REGR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-OROR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GORE | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GROR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKS1B-NDUFA12-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFA12 Gene Summary
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
Gene Name: NADH:ubiquinone Oxidoreductase Subunit A12
Chromosome: CHR12: 95365109 -95397511
Locus: 12q22
ANKS1B Gene Summary
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1B
Chromosome: CHR12: 99128568 -100378432
Locus: 12q23.1
Gene Diseases
The ANKS1B NDUFA12 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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