SEARCH OUR PRODUCT CATALOG

ANKS1B-PTPRQ Fusion FISH Probe

The ANKS1B-PTPRQ Fusion FISH Probe is used to confirm a fusion of the ANKS1B and PTPRQ genes. The fusion of the ANKS1B and PTPRQ genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ANKS1B-PTPRQ-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-RERE 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-REOR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-REGO 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-REGR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-REAQ 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-ORRE 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-OROR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-ORGO 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-ORAQ 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GORE 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GOOR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GOGO 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GOGR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GOAQ 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GRRE 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GROR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GRGO 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GRGR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-GRAQ 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-AQRE 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-AQOR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-AQGO 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-AQGR 20 (40 μL) 200 μL
ANKS1B-PTPRQ-20-AQAQ 20 (40 μL) 200 μL

ANKS1B Gene Summary

This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]

Gene Name: Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1B

Chromosome: CHR12: 99128568 -100378432

Locus: 12q23.1

PTPRQ Gene Summary

This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation. Mutations at this locus have been linked to autosomal recessive deafness. [provided by RefSeq, Mar 2014]

Gene Name: Protein Tyrosine Phosphatase, Receptor Type Q

Chromosome: CHR12: 80838125 -81073968

Locus: 12q21.31

Gene Diseases

The ANKS1B PTPRQ Fusion has been associated with the following diseases:

Disease Name
Mesothelioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.