ANO10-SCN5A Fusion FISH Probe
The ANO10-SCN5A Fusion FISH Probe is used to confirm a fusion of the ANO10 and SCN5A genes. The fusion of the ANO10 and SCN5A genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANO10-SCN5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-RERE | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-REOR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-REGO | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-REGR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-REAQ | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-ORRE | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-OROR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-ORGO | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GORE | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GOOR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GOGO | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GOGR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GRRE | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GROR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GRGO | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GRGR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-AQRE | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-AQOR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-AQGO | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-AQGR | 20 (40 μL) | 200 μL |
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| ANO10-SCN5A-20-AQAQ | 20 (40 μL) | 200 μL |
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SCN5A Gene Summary
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Sodium Voltage-gated Channel Alpha Subunit 5
Chromosome: CHR3: 38589552 -38691164
Locus: 3p22.2
ANO10 Gene Summary
The transmembrane protein encoded by this gene belongs to the anoctamin family of calcium-activated chloride channels, also known as the transmembrane 16 family. The encoded protein contains eight transmembrane domains with cytosolic N- and C-termini. Defects in this gene may cause autosomal recessive spinocerebellar ataxia-10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Name: Anoctamin 10
Chromosome: CHR3: 43407817 -43663560
Locus: 3p22.1-p21.33
Gene Diseases
The ANO10 SCN5A Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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