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ANO6-IAPP Fusion FISH Probe

The ANO6-IAPP Fusion FISH Probe is used to confirm a fusion of the ANO6 and IAPP genes. The fusion of the ANO6 and IAPP genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ANO6-IAPP-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ANO6-IAPP-20-RERE 20 (40 μL) 200 μL
ANO6-IAPP-20-REOR 20 (40 μL) 200 μL
ANO6-IAPP-20-REGO 20 (40 μL) 200 μL
ANO6-IAPP-20-REGR 20 (40 μL) 200 μL
ANO6-IAPP-20-REAQ 20 (40 μL) 200 μL
ANO6-IAPP-20-ORRE 20 (40 μL) 200 μL
ANO6-IAPP-20-OROR 20 (40 μL) 200 μL
ANO6-IAPP-20-ORGO 20 (40 μL) 200 μL
ANO6-IAPP-20-ORAQ 20 (40 μL) 200 μL
ANO6-IAPP-20-GORE 20 (40 μL) 200 μL
ANO6-IAPP-20-GOOR 20 (40 μL) 200 μL
ANO6-IAPP-20-GOGO 20 (40 μL) 200 μL
ANO6-IAPP-20-GOGR 20 (40 μL) 200 μL
ANO6-IAPP-20-GOAQ 20 (40 μL) 200 μL
ANO6-IAPP-20-GRRE 20 (40 μL) 200 μL
ANO6-IAPP-20-GROR 20 (40 μL) 200 μL
ANO6-IAPP-20-GRGO 20 (40 μL) 200 μL
ANO6-IAPP-20-GRGR 20 (40 μL) 200 μL
ANO6-IAPP-20-GRAQ 20 (40 μL) 200 μL
ANO6-IAPP-20-AQRE 20 (40 μL) 200 μL
ANO6-IAPP-20-AQOR 20 (40 μL) 200 μL
ANO6-IAPP-20-AQGO 20 (40 μL) 200 μL
ANO6-IAPP-20-AQGR 20 (40 μL) 200 μL
ANO6-IAPP-20-AQAQ 20 (40 μL) 200 μL

IAPP Gene Summary

This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]

Gene Name: Islet Amyloid Polypeptide

Chromosome: CHR12: 21525801 -21532914

Locus: 12p12.1

ANO6 Gene Summary

This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

Gene Name: Anoctamin 6

Chromosome: CHR12: 45609769 -45834187

Locus: 12q12

Gene Diseases

The ANO6 IAPP Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.