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AP1M1-CYP4F11 Fusion FISH Probe

The AP1M1-CYP4F11 Fusion FISH Probe is used to confirm a fusion of the AP1M1 and CYP4F11 genes. The fusion of the AP1M1 and CYP4F11 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AP1M1-CYP4F11-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-RERE 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-REOR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-REGO 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-REGR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-REAQ 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-ORRE 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-OROR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-ORGO 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-ORAQ 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GORE 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GOOR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GOGO 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GOGR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GOAQ 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GRRE 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GROR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GRGO 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GRGR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-GRAQ 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-AQRE 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-AQOR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-AQGO 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-AQGR 20 (40 μL) 200 μL
AP1M1-CYP4F11-20-AQAQ 20 (40 μL) 200 μL

AP1M1 Gene Summary

The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Adaptor Related Protein Complex 1 Mu 1 Subunit

Chromosome: CHR19: 16308664 -16346156

Locus: 19p13.11

CYP4F11 Gene Summary

This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Cytochrome P450 Family 4 Subfamily F Member 11

Chromosome: CHR19: 16023179 -16045676

Locus: 19p13.12

Gene Diseases

The AP1M1 CYP4F11 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.