AP2A2-VPS26A Fusion FISH Probe
The AP2A2-VPS26A Fusion FISH Probe is used to confirm a fusion of the AP2A2 and VPS26A genes. The fusion of the AP2A2 and VPS26A genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP2A2-VPS26A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-RERE | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-REOR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-REGO | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-REGR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-REAQ | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-ORRE | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-OROR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-ORGO | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GORE | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GOOR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GOGO | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GOGR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GRRE | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GROR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GRGO | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GRGR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-AQRE | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-AQOR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-AQGO | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-AQGR | 20 (40 μL) | 200 μL |
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| AP2A2-VPS26A-20-AQAQ | 20 (40 μL) | 200 μL |
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AP2A2 Gene Summary
The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016]
Gene Name: Adaptor Related Protein Complex 2 Alpha 2 Subunit
Chromosome: CHR11: 925808 -1012245
Locus: 11p15.5
VPS26A Gene Summary
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: VPS26, Retromer Complex Component A
Chromosome: CHR10: 70883907 -70932616
Locus: 10q22.1
Gene Diseases
The AP2A2 VPS26A Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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