AP3B1-LHFPL2 Fusion FISH Probe
The AP3B1-LHFPL2 Fusion FISH Probe is used to confirm a fusion of the AP3B1 and LHFPL2 genes. The fusion of the AP3B1 and LHFPL2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP3B1-LHFPL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AP3B1-LHFPL2-20-AQAQ | 20 (40 μL) | 200 μL |
|
AP3B1 Gene Summary
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Name: Adaptor Related Protein Complex 3 Beta 1 Subunit
Chromosome: CHR5: 77298149 -77590528
Locus: 5q14.1
LHFPL2 Gene Summary
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: LHFPL Tetraspan Subfamily Member 2
Chromosome: CHR5: 77781037 -77944648
Locus: 5q14.1
Gene Diseases
The AP3B1 LHFPL2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|