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APBA2-SOAT2 Fusion FISH Probe

The APBA2-SOAT2 Fusion FISH Probe is used to confirm a fusion of the APBA2 and SOAT2 genes. The fusion of the APBA2 and SOAT2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
APBA2-SOAT2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
APBA2-SOAT2-20-RERE 20 (40 μL) 200 μL
APBA2-SOAT2-20-REOR 20 (40 μL) 200 μL
APBA2-SOAT2-20-REGO 20 (40 μL) 200 μL
APBA2-SOAT2-20-REGR 20 (40 μL) 200 μL
APBA2-SOAT2-20-REAQ 20 (40 μL) 200 μL
APBA2-SOAT2-20-ORRE 20 (40 μL) 200 μL
APBA2-SOAT2-20-OROR 20 (40 μL) 200 μL
APBA2-SOAT2-20-ORGO 20 (40 μL) 200 μL
APBA2-SOAT2-20-ORAQ 20 (40 μL) 200 μL
APBA2-SOAT2-20-GORE 20 (40 μL) 200 μL
APBA2-SOAT2-20-GOOR 20 (40 μL) 200 μL
APBA2-SOAT2-20-GOGO 20 (40 μL) 200 μL
APBA2-SOAT2-20-GOGR 20 (40 μL) 200 μL
APBA2-SOAT2-20-GOAQ 20 (40 μL) 200 μL
APBA2-SOAT2-20-GRRE 20 (40 μL) 200 μL
APBA2-SOAT2-20-GROR 20 (40 μL) 200 μL
APBA2-SOAT2-20-GRGO 20 (40 μL) 200 μL
APBA2-SOAT2-20-GRGR 20 (40 μL) 200 μL
APBA2-SOAT2-20-GRAQ 20 (40 μL) 200 μL
APBA2-SOAT2-20-AQRE 20 (40 μL) 200 μL
APBA2-SOAT2-20-AQOR 20 (40 μL) 200 μL
APBA2-SOAT2-20-AQGO 20 (40 μL) 200 μL
APBA2-SOAT2-20-AQGR 20 (40 μL) 200 μL
APBA2-SOAT2-20-AQAQ 20 (40 μL) 200 μL

APBA2 Gene Summary

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]

Gene Name: Amyloid Beta Precursor Protein Binding Family A Member 2

Chromosome: CHR15: 29213839 -29410516

Locus: 15q13.1

SOAT2 Gene Summary

Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Gene Name: Sterol O-acyltransferase 2

Chromosome: CHR12: 53497273 -53518323

Locus: 12q13.13

Gene Diseases

The APBA2 SOAT2 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.