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APC-C5ORF13 Fusion FISH Probe

The APC-C5ORF13 Fusion FISH Probe is used to confirm a fusion of the APC and C5ORF13 genes. The fusion of the APC and C5ORF13 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
APC-C5ORF13-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
APC-C5ORF13-20-RERE 20 (40 μL) 200 μL
APC-C5ORF13-20-REOR 20 (40 μL) 200 μL
APC-C5ORF13-20-REGO 20 (40 μL) 200 μL
APC-C5ORF13-20-REGR 20 (40 μL) 200 μL
APC-C5ORF13-20-REAQ 20 (40 μL) 200 μL
APC-C5ORF13-20-ORRE 20 (40 μL) 200 μL
APC-C5ORF13-20-OROR 20 (40 μL) 200 μL
APC-C5ORF13-20-ORGO 20 (40 μL) 200 μL
APC-C5ORF13-20-ORAQ 20 (40 μL) 200 μL
APC-C5ORF13-20-GORE 20 (40 μL) 200 μL
APC-C5ORF13-20-GOOR 20 (40 μL) 200 μL
APC-C5ORF13-20-GOGO 20 (40 μL) 200 μL
APC-C5ORF13-20-GOGR 20 (40 μL) 200 μL
APC-C5ORF13-20-GOAQ 20 (40 μL) 200 μL
APC-C5ORF13-20-GRRE 20 (40 μL) 200 μL
APC-C5ORF13-20-GROR 20 (40 μL) 200 μL
APC-C5ORF13-20-GRGO 20 (40 μL) 200 μL
APC-C5ORF13-20-GRGR 20 (40 μL) 200 μL
APC-C5ORF13-20-GRAQ 20 (40 μL) 200 μL
APC-C5ORF13-20-AQRE 20 (40 μL) 200 μL
APC-C5ORF13-20-AQOR 20 (40 μL) 200 μL
APC-C5ORF13-20-AQGO 20 (40 μL) 200 μL
APC-C5ORF13-20-AQGR 20 (40 μL) 200 μL
APC-C5ORF13-20-AQAQ 20 (40 μL) 200 μL

APC Gene Summary

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]

Gene Name: APC, WNT Signaling Pathway Regulator

Chromosome: CHR5: 112043201 -112181936

Locus: 5q22.2

Gene Diseases

The APC C5ORF13 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.