APC-SLC27A6 Fusion FISH Probe
The APC-SLC27A6 Fusion FISH Probe is used to confirm a fusion of the APC and SLC27A6 genes. The fusion of the APC and SLC27A6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APC-SLC27A6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-RERE | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-REOR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-REGO | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-REGR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-REAQ | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-ORRE | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-OROR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-ORGO | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-ORAQ | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GORE | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GOOR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GOGO | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GOGR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GOAQ | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GRRE | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GROR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GRGO | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GRGR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-GRAQ | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-AQRE | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-AQOR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-AQGO | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-AQGR | 20 (40 μL) | 200 μL |
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| APC-SLC27A6-20-AQAQ | 20 (40 μL) | 200 μL |
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APC Gene Summary
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Gene Name: APC, WNT Signaling Pathway Regulator
Chromosome: CHR5: 112043201 -112181936
Locus: 5q22.2
SLC27A6 Gene Summary
This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 27 Member 6
Chromosome: CHR5: 128301209 -128369335
Locus: 5q23.3
Gene Diseases
The APC SLC27A6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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