APPL1-SPATA12 Fusion FISH Probe
The APPL1-SPATA12 Fusion FISH Probe is used to confirm a fusion of the APPL1 and SPATA12 genes. The fusion of the APPL1 and SPATA12 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APPL1-SPATA12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-RERE | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-REOR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-REGO | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-REGR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-REAQ | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-ORRE | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-OROR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-ORGO | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-ORAQ | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GORE | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GOOR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GOGO | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GOGR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GOAQ | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GRRE | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GROR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GRGO | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GRGR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-GRAQ | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-AQRE | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-AQOR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-AQGO | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-AQGR | 20 (40 μL) | 200 μL |
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| APPL1-SPATA12-20-AQAQ | 20 (40 μL) | 200 μL |
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APPL1 Gene Summary
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Protein, Phosphotyrosine Interacting With PH Domain And Leucine Zipper 1
Chromosome: CHR3: 57261764 -57307498
Locus: 3p14.3
SPATA12 Gene Summary
This gene is expressed primarily in testis and may play a role in testicular development and spermatogenesis. The encoded protein may be upregulated in response to ultraviolet-C radiation. [provided by RefSeq, Dec 2015]
Gene Name: Spermatogenesis Associated 12
Chromosome: CHR3: 57094468 -57109460
Locus: 3p14.3
Gene Diseases
The APPL1 SPATA12 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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