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ARFGAP3-PACSIN2 Fusion FISH Probe

The ARFGAP3-PACSIN2 Fusion FISH Probe is used to confirm a fusion of the ARFGAP3 and PACSIN2 genes. The fusion of the ARFGAP3 and PACSIN2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ARFGAP3-PACSIN2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-RERE 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-REOR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-REGO 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-REGR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-REAQ 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-ORRE 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-OROR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-ORGO 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-ORAQ 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GORE 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GOOR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GOGO 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GOGR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GOAQ 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GRRE 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GROR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GRGO 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GRGR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-GRAQ 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-AQRE 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-AQOR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-AQGO 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-AQGR 20 (40 μL) 200 μL
ARFGAP3-PACSIN2-20-AQAQ 20 (40 μL) 200 μL

PACSIN2 Gene Summary

This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Gene Name: Protein Kinase C And Casein Kinase Substrate In Neurons 2

Chromosome: CHR22: 43265771 -43411184

Locus: 22q13.2

ARFGAP3 Gene Summary

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]

Gene Name: ADP Ribosylation Factor GTPase Activating Protein 3

Chromosome: CHR22: 43192531 -43253408

Locus: 22q13.2

Gene Diseases

The ARFGAP3 PACSIN2 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.