ARFGEF1-CSPP1 Fusion FISH Probe
The ARFGEF1-CSPP1 Fusion FISH Probe is used to confirm a fusion of the ARFGEF1 and CSPP1 genes. The fusion of the ARFGEF1 and CSPP1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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ARFGEF1-CSPP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-RERE | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-REOR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-REGO | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-REGR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-REAQ | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-ORRE | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-OROR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-ORGO | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-ORAQ | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GORE | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GOOR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GOGO | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GOGR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GOAQ | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GRRE | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GROR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GRGO | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GRGR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-GRAQ | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-AQRE | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-AQOR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-AQGO | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-AQGR | 20 (40 μL) | 200 μL |
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ARFGEF1-CSPP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ARFGEF1 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Aug 2011]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1
Chromosome: CHR8: 68109883 -68255912
Locus: 8q13.2
CSPP1 Gene Summary
This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Centrosome And Spindle Pole Associated Protein 1
Chromosome: CHR8: 67976602 -68108849
Locus: 8q13.1-q13.2
Gene Diseases
The ARFGEF1 CSPP1 Fusion has been associated with the following diseases:
Disease Name |
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Colon Adenocarcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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