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ARFGEF1-CSPP1 Fusion FISH Probe

The ARFGEF1-CSPP1 Fusion FISH Probe is used to confirm a fusion of the ARFGEF1 and CSPP1 genes. The fusion of the ARFGEF1 and CSPP1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ARFGEF1-CSPP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-RERE 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-REOR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-REGO 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-REGR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-REAQ 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-ORRE 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-OROR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-ORGO 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-ORAQ 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GORE 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GOOR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GOGO 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GOGR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GOAQ 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GRRE 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GROR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GRGO 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GRGR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-GRAQ 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-AQRE 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-AQOR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-AQGO 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-AQGR 20 (40 μL) 200 μL
ARFGEF1-CSPP1-20-AQAQ 20 (40 μL) 200 μL

ARFGEF1 Gene Summary

ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Aug 2011]

Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 1

Chromosome: CHR8: 68109883 -68255912

Locus: 8q13.2

CSPP1 Gene Summary

This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Gene Name: Centrosome And Spindle Pole Associated Protein 1

Chromosome: CHR8: 67976602 -68108849

Locus: 8q13.1-q13.2

Gene Diseases

The ARFGEF1 CSPP1 Fusion has been associated with the following diseases:

Disease Name
Colon Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.