ARFIP1-FGB Fusion FISH Probe
The ARFIP1-FGB Fusion FISH Probe is used to confirm a fusion of the ARFIP1 and FGB genes. The fusion of the ARFIP1 and FGB genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARFIP1-FGB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-RERE | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-REOR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-REGO | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-REGR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-REAQ | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-ORRE | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-OROR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-ORGO | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GORE | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GOOR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GOGO | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GOGR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GRRE | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GROR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GRGO | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GRGR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-AQRE | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-AQOR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-AQGO | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-AQGR | 20 (40 μL) | 200 μL |
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| ARFIP1-FGB-20-AQAQ | 20 (40 μL) | 200 μL |
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FGB Gene Summary
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Name: Fibrinogen Beta Chain
Chromosome: CHR4: 155484131 -155493915
Locus: 4q31.3
ARFIP1 Gene Summary
The ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) gene is located on chr4 :153701111-153833063 at 4q31.3.
Gene Name: ADP Ribosylation Factor Interacting Protein 1
Chromosome: CHR4: 153701111 -153833063
Locus: 4q31.3
Gene Diseases
The ARFIP1 FGB Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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