ARHGAP19-CYB5A Fusion FISH Probe
The ARHGAP19-CYB5A Fusion FISH Probe is used to confirm a fusion of the ARHGAP19 and CYB5A genes. The fusion of the ARHGAP19 and CYB5A genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP19-CYB5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP19-CYB5A-20-AQAQ | 20 (40 μL) | 200 μL |
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CYB5A Gene Summary
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Name: Cytochrome B5 Type A
Chromosome: CHR18: 71920526 -71959251
Locus: 18q22.3
ARHGAP19 Gene Summary
Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression (Lv et al., 2007 [PubMed 17454002]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 19
Chromosome: CHR10: 98981929 -99052430
Locus: 10q24.1
Gene Diseases
The ARHGAP19 CYB5A Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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