ARHGAP23-CCL18 Fusion FISH Probe
The ARHGAP23-CCL18 Fusion FISH Probe is used to confirm a fusion of the ARHGAP23 and CCL18 genes. The fusion of the ARHGAP23 and CCL18 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP23-CCL18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP23-CCL18-20-AQAQ | 20 (40 μL) | 200 μL |
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CCL18 Gene Summary
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
Gene Name: C-C Motif Chemokine Ligand 18
Chromosome: CHR17: 34391642 -34398841
Locus: 17q12
ARHGAP23 Gene Summary
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 23
Chromosome: CHR17: 36584719 -36668628
Locus: 17q12
Gene Diseases
The ARHGAP23 CCL18 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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