ARHGAP23-CCR7 Fusion FISH Probe
The ARHGAP23-CCR7 Fusion FISH Probe is used to confirm a fusion of the ARHGAP23 and CCR7 genes. The fusion of the ARHGAP23 and CCR7 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGAP23-CCR7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ARHGAP23-CCR7-20-AQAQ | 20 (40 μL) | 200 μL |
|
CCR7 Gene Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Name: C-C Motif Chemokine Receptor 7
Chromosome: CHR17: 38710021 -38721736
Locus: 17q21.2
ARHGAP23 Gene Summary
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 23
Chromosome: CHR17: 36584719 -36668628
Locus: 17q12
Gene Diseases
The ARHGAP23 CCR7 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|