ARHGAP29-DNAJC6 Fusion FISH Probe
The ARHGAP29-DNAJC6 Fusion FISH Probe is used to confirm a fusion of the ARHGAP29 and DNAJC6 genes. The fusion of the ARHGAP29 and DNAJC6 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP29-DNAJC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-DNAJC6-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP29 Gene Summary
Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]
Gene Name: Rho GTPase Activating Protein 29
Chromosome: CHR1: 94634462 -94703307
Locus: 1p22.1
DNAJC6 Gene Summary
DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C6
Chromosome: CHR1: 65730429 -65881552
Locus: 1p31.3
Gene Diseases
The ARHGAP29 DNAJC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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