ARHGAP42-KMO Fusion FISH Probe
The ARHGAP42-KMO Fusion FISH Probe is used to confirm a fusion of the ARHGAP42 and KMO genes. The fusion of the ARHGAP42 and KMO genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP42-KMO-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-KMO-20-AQAQ | 20 (40 μL) | 200 μL |
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KMO Gene Summary
This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011]
Gene Name: Kynurenine 3-monooxygenase
Chromosome: CHR1: 241695679 -241758944
Locus: 1q43
ARHGAP42 Gene Summary
This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
Gene Name: Rho GTPase Activating Protein 42
Chromosome: CHR11: 100558406 -100861656
Locus: 11q22.1
Gene Diseases
The ARHGAP42 KMO Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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