ARHGAP42-SBF2 Fusion FISH Probe
The ARHGAP42-SBF2 Fusion FISH Probe is used to confirm a fusion of the ARHGAP42 and SBF2 genes. The fusion of the ARHGAP42 and SBF2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP42-SBF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP42-SBF2-20-AQAQ | 20 (40 μL) | 200 μL |
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SBF2 Gene Summary
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
Gene Name: SET Binding Factor 2
Chromosome: CHR11: 9800213 -10315754
Locus: 11p15.4
ARHGAP42 Gene Summary
This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
Gene Name: Rho GTPase Activating Protein 42
Chromosome: CHR11: 100558406 -100861656
Locus: 11q22.1
Gene Diseases
The ARHGAP42 SBF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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