ARHGDIA-SQSTM1 Fusion FISH Probe
The ARHGDIA-SQSTM1 Fusion FISH Probe is used to confirm a fusion of the ARHGDIA and SQSTM1 genes. The fusion of the ARHGDIA and SQSTM1 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGDIA-SQSTM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-SQSTM1-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGDIA Gene Summary
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: Rho GDP Dissociation Inhibitor Alpha
Chromosome: CHR17: 79825596 -79829282
Locus: 17q25.3
SQSTM1 Gene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Gene Name: Sequestosome 1
Chromosome: CHR5: 179233387 -179265077
Locus: 5q35.3
Gene Diseases
The ARHGDIA SQSTM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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