ARHGEF17-EP300 Fusion FISH Probe
The ARHGEF17-EP300 Fusion FISH Probe is used to confirm a fusion of the ARHGEF17 and EP300 genes. The fusion of the ARHGEF17 and EP300 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF17-EP300-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-EP300-20-AQAQ | 20 (40 μL) | 200 μL |
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EP300 Gene Summary
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Gene Name: E1A Binding Protein P300
Chromosome: CHR22: 41488613 -41576081
Locus: 22q13.2
ARHGEF17 Gene Summary
The Rho Guanine Nucleotide Exchange Factor 17 (ARHGEF17) gene is located on chr11 :73019662-73080425 at 11q13.4.
Gene Name: Rho Guanine Nucleotide Exchange Factor 17
Chromosome: CHR11: 73019662 -73080425
Locus: 11q13.4
Gene Diseases
The ARHGEF17 EP300 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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