ARHGEF17-P2RY2 Fusion FISH Probe
The ARHGEF17-P2RY2 Fusion FISH Probe is used to confirm a fusion of the ARHGEF17 and P2RY2 genes. The fusion of the ARHGEF17 and P2RY2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF17-P2RY2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF17-P2RY2-20-AQAQ | 20 (40 μL) | 200 μL |
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P2RY2 Gene Summary
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]
Gene Name: Purinergic Receptor P2Y2
Chromosome: CHR11: 72929343 -72947395
Locus: 11q13.4
ARHGEF17 Gene Summary
The Rho Guanine Nucleotide Exchange Factor 17 (ARHGEF17) gene is located on chr11 :73019662-73080425 at 11q13.4.
Gene Name: Rho Guanine Nucleotide Exchange Factor 17
Chromosome: CHR11: 73019662 -73080425
Locus: 11q13.4
Gene Diseases
The ARHGEF17 P2RY2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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