ARHGEF2-S100A7 Fusion FISH Probe
The ARHGEF2-S100A7 Fusion FISH Probe is used to confirm a fusion of the ARHGEF2 and S100A7 genes. The fusion of the ARHGEF2 and S100A7 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF2-S100A7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF2-S100A7-20-AQAQ | 20 (40 μL) | 200 μL |
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S100A7 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
Gene Name: S100 Calcium Binding Protein A7
Chromosome: CHR1: 153430219 -153433137
Locus: 1q21.3
ARHGEF2 Gene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]
Gene Name: Rho/Rac Guanine Nucleotide Exchange Factor 2
Chromosome: CHR1: 155916629 -155948336
Locus: 1q22
Gene Diseases
The ARHGEF2 S100A7 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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