ARHGEF3-CTNND2 Fusion FISH Probe
The ARHGEF3-CTNND2 Fusion FISH Probe is used to confirm a fusion of the ARHGEF3 and CTNND2 genes. The fusion of the ARHGEF3 and CTNND2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF3-CTNND2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-CTNND2-20-AQAQ | 20 (40 μL) | 200 μL |
|
CTNND2 Gene Summary
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Gene Name: Catenin Delta 2
Chromosome: CHR5: 10971951 -11904110
Locus: 5p15.2
ARHGEF3 Gene Summary
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Rho Guanine Nucleotide Exchange Factor 3
Chromosome: CHR3: 56761445 -57113336
Locus: 3p14.3
Gene Diseases
The ARHGEF3 CTNND2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|