ARHGEF7-EXOC4 Fusion FISH Probe
The ARHGEF7-EXOC4 Fusion FISH Probe is used to confirm a fusion of the ARHGEF7 and EXOC4 genes. The fusion of the ARHGEF7 and EXOC4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF7-EXOC4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-EXOC4-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGEF7 Gene Summary
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Rho Guanine Nucleotide Exchange Factor 7
Chromosome: CHR13: 111767623 -111947542
Locus: 13q34
EXOC4 Gene Summary
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Exocyst Complex Component 4
Chromosome: CHR7: 132937822 -133750513
Locus: 7q33
Gene Diseases
The ARHGEF7 EXOC4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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