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ARHGEF7-PKIB Fusion FISH Probe

The ARHGEF7-PKIB Fusion FISH Probe is used to confirm a fusion of the ARHGEF7 and PKIB genes. The fusion of the ARHGEF7 and PKIB genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ARHGEF7-PKIB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-RERE 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-REOR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-REGO 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-REGR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-REAQ 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-ORRE 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-OROR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-ORGO 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-ORAQ 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GORE 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GOOR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GOGO 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GOGR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GOAQ 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GRRE 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GROR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GRGO 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GRGR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-GRAQ 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-AQRE 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-AQOR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-AQGO 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-AQGR 20 (40 μL) 200 μL
ARHGEF7-PKIB-20-AQAQ 20 (40 μL) 200 μL

PKIB Gene Summary

This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Gene Name: CAMP-dependent Protein Kinase Inhibitor Beta

Chromosome: CHR6: 122793061 -123047518

Locus: 6q22.31

ARHGEF7 Gene Summary

This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]

Gene Name: Rho Guanine Nucleotide Exchange Factor 7

Chromosome: CHR13: 111767623 -111947542

Locus: 13q34

Gene Diseases

The ARHGEF7 PKIB Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.