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ARID1A-DHDDS Fusion FISH Probe

The ARID1A-DHDDS Fusion FISH Probe is used to confirm a fusion of the ARID1A and DHDDS genes. The fusion of the ARID1A and DHDDS genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ARID1A-DHDDS-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ARID1A-DHDDS-20-RERE 20 (40 μL) 200 μL
ARID1A-DHDDS-20-REOR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-REGO 20 (40 μL) 200 μL
ARID1A-DHDDS-20-REGR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-REAQ 20 (40 μL) 200 μL
ARID1A-DHDDS-20-ORRE 20 (40 μL) 200 μL
ARID1A-DHDDS-20-OROR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-ORGO 20 (40 μL) 200 μL
ARID1A-DHDDS-20-ORAQ 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GORE 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GOOR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GOGO 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GOGR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GOAQ 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GRRE 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GROR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GRGO 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GRGR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-GRAQ 20 (40 μL) 200 μL
ARID1A-DHDDS-20-AQRE 20 (40 μL) 200 μL
ARID1A-DHDDS-20-AQOR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-AQGO 20 (40 μL) 200 μL
ARID1A-DHDDS-20-AQGR 20 (40 μL) 200 μL
ARID1A-DHDDS-20-AQAQ 20 (40 μL) 200 μL

ARID1A Gene Summary

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: AT-rich Interaction Domain 1A

Chromosome: CHR1: 27022521 -27108601

Locus: 1p36.11

DHDDS Gene Summary

The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Gene Name: Dehydrodolichyl Diphosphate Synthase Subunit

Chromosome: CHR1: 26758772 -26797795

Locus: 1p36.11

Gene Diseases

The ARID1A DHDDS Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.