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ARID1B-TIAM2 Fusion FISH Probe

The ARID1B-TIAM2 Fusion FISH Probe is used to confirm a fusion of the ARID1B and TIAM2 genes. The fusion of the ARID1B and TIAM2 genes has been associated with Glioblastoma Multiforme, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ARID1B-TIAM2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ARID1B-TIAM2-20-RERE 20 (40 μL) 200 μL
ARID1B-TIAM2-20-REOR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-REGO 20 (40 μL) 200 μL
ARID1B-TIAM2-20-REGR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-REAQ 20 (40 μL) 200 μL
ARID1B-TIAM2-20-ORRE 20 (40 μL) 200 μL
ARID1B-TIAM2-20-OROR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-ORGO 20 (40 μL) 200 μL
ARID1B-TIAM2-20-ORAQ 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GORE 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GOOR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GOGO 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GOGR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GOAQ 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GRRE 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GROR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GRGO 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GRGR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-GRAQ 20 (40 μL) 200 μL
ARID1B-TIAM2-20-AQRE 20 (40 μL) 200 μL
ARID1B-TIAM2-20-AQOR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-AQGO 20 (40 μL) 200 μL
ARID1B-TIAM2-20-AQGR 20 (40 μL) 200 μL
ARID1B-TIAM2-20-AQAQ 20 (40 μL) 200 μL

TIAM2 Gene Summary

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Name: T-cell Lymphoma Invasion And Metastasis 2

Chromosome: CHR6: 155411422 -155578857

Locus: 6q25.2-q25.3

ARID1B Gene Summary

This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Gene Name: AT-rich Interaction Domain 1B

Chromosome: CHR6: 157099063 -157531913

Locus: 6q25.3

Gene Diseases

The ARID1B TIAM2 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.