ARID2-TMPRSS2 Fusion FISH Probe
The ARID2-TMPRSS2 Fusion FISH Probe is used to confirm a fusion of the ARID2 and TMPRSS2 genes. The fusion of the ARID2 and TMPRSS2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARID2-TMPRSS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-RERE | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-REOR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-REGO | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-REGR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-REAQ | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-ORRE | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-OROR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-ORGO | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GORE | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GOOR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GOGO | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GOGR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GRRE | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GROR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GRGO | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GRGR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-AQRE | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-AQOR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-AQGO | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-AQGR | 20 (40 μL) | 200 μL |
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| ARID2-TMPRSS2-20-AQAQ | 20 (40 μL) | 200 μL |
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TMPRSS2 Gene Summary
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Name: Transmembrane Protease, Serine 2
Chromosome: CHR21: 42836477 -42880085
Locus: 21q22.3
ARID2 Gene Summary
This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1. [provided by RefSeq, Dec 2016]
Gene Name: AT-rich Interaction Domain 2
Chromosome: CHR12: 46123619 -46301819
Locus: 12q12
Gene Diseases
The ARID2 TMPRSS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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