ARIH2-DHX30 Fusion FISH Probe
The ARIH2-DHX30 Fusion FISH Probe is used to confirm a fusion of the ARIH2 and DHX30 genes. The fusion of the ARIH2 and DHX30 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARIH2-DHX30-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-RERE | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-REOR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-REGO | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-REGR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-REAQ | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-ORRE | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-OROR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-ORGO | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GORE | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GOOR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GOGO | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GOGR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GRRE | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GROR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GRGO | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GRGR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-AQRE | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-AQOR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-AQGO | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-AQGR | 20 (40 μL) | 200 μL |
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| ARIH2-DHX30-20-AQAQ | 20 (40 μL) | 200 μL |
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ARIH2 Gene Summary
The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet. [provided by RefSeq, Nov 2015]
Gene Name: Ariadne RBR E3 Ubiquitin Protein Ligase 2
Chromosome: CHR3: 48956280 -49022971
Locus: 3p21.31
DHX30 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: DExH-box Helicase 30
Chromosome: CHR3: 47844398 -47891686
Locus: 3p21.31
Gene Diseases
The ARIH2 DHX30 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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