ARIH2-TRIO Fusion FISH Probe
The ARIH2-TRIO Fusion FISH Probe is used to confirm a fusion of the ARIH2 and TRIO genes. The fusion of the ARIH2 and TRIO genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARIH2-TRIO-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-RERE | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-REOR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-REGO | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-REGR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-REAQ | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-ORRE | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-OROR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-ORGO | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GORE | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GOOR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GOGO | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GOGR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GRRE | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GROR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GRGO | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GRGR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-AQRE | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-AQOR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-AQGO | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-AQGR | 20 (40 μL) | 200 μL |
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| ARIH2-TRIO-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIO Gene Summary
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Trio Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR5: 14143828 -14509458
Locus: 5p15.2
ARIH2 Gene Summary
The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet. [provided by RefSeq, Nov 2015]
Gene Name: Ariadne RBR E3 Ubiquitin Protein Ligase 2
Chromosome: CHR3: 48956280 -49022971
Locus: 3p21.31
Gene Diseases
The ARIH2 TRIO Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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