ARNTL-RIC8B Fusion FISH Probe
The ARNTL-RIC8B Fusion FISH Probe is used to confirm a fusion of the ARNTL and RIC8B genes. The fusion of the ARNTL and RIC8B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARNTL-RIC8B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-RERE | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-REOR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-REGO | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-REGR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-REAQ | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-ORRE | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-OROR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-ORGO | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GORE | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GOOR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GOGO | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GOGR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GRRE | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GROR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GRGO | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GRGR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-AQRE | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-AQOR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-AQGO | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-AQGR | 20 (40 μL) | 200 μL |
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| ARNTL-RIC8B-20-AQAQ | 20 (40 μL) | 200 μL |
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ARNTL Gene Summary
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: Aryl Hydrocarbon Receptor Nuclear Translocator Like
Chromosome: CHR11: 13299324 -13408812
Locus: 11p15.3
RIC8B Gene Summary
The RIC8 Guanine Nucleotide Exchange Factor B (RIC8B) gene is located on chr12 :107168398-107283094 at 12q23.3.
Gene Name: RIC8 Guanine Nucleotide Exchange Factor B
Chromosome: CHR12: 107168398 -107283094
Locus: 12q23.3
Gene Diseases
The ARNTL RIC8B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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