ARRB1-LY9 Fusion FISH Probe
The ARRB1-LY9 Fusion FISH Probe is used to confirm a fusion of the ARRB1 and LY9 genes. The fusion of the ARRB1 and LY9 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARRB1-LY9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-RERE | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-REOR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-REGO | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-REGR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-REAQ | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-ORRE | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-OROR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-ORGO | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GORE | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GOOR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GOGO | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GOGR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GRRE | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GROR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GRGO | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GRGR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-AQRE | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-AQOR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-AQGO | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-AQGR | 20 (40 μL) | 200 μL |
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| ARRB1-LY9-20-AQAQ | 20 (40 μL) | 200 μL |
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ARRB1 Gene Summary
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Gene Name: Arrestin Beta 1
Chromosome: CHR11: 74971165 -75062875
Locus: 11q13.4
LY9 Gene Summary
LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008]
Gene Name: Lymphocyte Antigen 9
Chromosome: CHR1: 160765927 -160798045
Locus: 1q23.3
Gene Diseases
The ARRB1 LY9 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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