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ASCC3-WASF1 Fusion FISH Probe

The ASCC3-WASF1 Fusion FISH Probe is used to confirm a fusion of the ASCC3 and WASF1 genes. The fusion of the ASCC3 and WASF1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ASCC3-WASF1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ASCC3-WASF1-20-RERE 20 (40 μL) 200 μL
ASCC3-WASF1-20-REOR 20 (40 μL) 200 μL
ASCC3-WASF1-20-REGO 20 (40 μL) 200 μL
ASCC3-WASF1-20-REGR 20 (40 μL) 200 μL
ASCC3-WASF1-20-REAQ 20 (40 μL) 200 μL
ASCC3-WASF1-20-ORRE 20 (40 μL) 200 μL
ASCC3-WASF1-20-OROR 20 (40 μL) 200 μL
ASCC3-WASF1-20-ORGO 20 (40 μL) 200 μL
ASCC3-WASF1-20-ORAQ 20 (40 μL) 200 μL
ASCC3-WASF1-20-GORE 20 (40 μL) 200 μL
ASCC3-WASF1-20-GOOR 20 (40 μL) 200 μL
ASCC3-WASF1-20-GOGO 20 (40 μL) 200 μL
ASCC3-WASF1-20-GOGR 20 (40 μL) 200 μL
ASCC3-WASF1-20-GOAQ 20 (40 μL) 200 μL
ASCC3-WASF1-20-GRRE 20 (40 μL) 200 μL
ASCC3-WASF1-20-GROR 20 (40 μL) 200 μL
ASCC3-WASF1-20-GRGO 20 (40 μL) 200 μL
ASCC3-WASF1-20-GRGR 20 (40 μL) 200 μL
ASCC3-WASF1-20-GRAQ 20 (40 μL) 200 μL
ASCC3-WASF1-20-AQRE 20 (40 μL) 200 μL
ASCC3-WASF1-20-AQOR 20 (40 μL) 200 μL
ASCC3-WASF1-20-AQGO 20 (40 μL) 200 μL
ASCC3-WASF1-20-AQGR 20 (40 μL) 200 μL
ASCC3-WASF1-20-AQAQ 20 (40 μL) 200 μL

WASF1 Gene Summary

The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: WAS Protein Family Member 1

Chromosome: CHR6: 110421021 -110501207

Locus: 6q21

ASCC3 Gene Summary

This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Name: Activating Signal Cointegrator 1 Complex Subunit 3

Chromosome: CHR6: 100956607 -101329224

Locus: 6q16.3

Gene Diseases

The ASCC3 WASF1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.