ATF3-USH2A Fusion FISH Probe
The ATF3-USH2A Fusion FISH Probe is used to confirm a fusion of the ATF3 and USH2A genes. The fusion of the ATF3 and USH2A genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATF3-USH2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-RERE | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-REOR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-REGO | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-REGR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-REAQ | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-ORRE | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-OROR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-ORGO | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GORE | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GOOR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GOGO | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GOGR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GRRE | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GROR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GRGO | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GRGR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-AQRE | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-AQOR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-AQGO | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-AQGR | 20 (40 μL) | 200 μL |
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| ATF3-USH2A-20-AQAQ | 20 (40 μL) | 200 μL |
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ATF3 Gene Summary
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]
Gene Name: Activating Transcription Factor 3
Chromosome: CHR1: 212738675 -212794119
Locus: 1q32.3
USH2A Gene Summary
This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Usherin
Chromosome: CHR1: 215796235 -216596738
Locus: 1q41
Gene Diseases
The ATF3 USH2A Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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