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ATF6-ODZ3 Fusion FISH Probe

The ATF6-ODZ3 Fusion FISH Probe is used to confirm a fusion of the ATF6 and ODZ3 genes. The fusion of the ATF6 and ODZ3 genes has been associated with Sarcoma, and Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ATF6-ODZ3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ATF6-ODZ3-20-RERE 20 (40 μL) 200 μL
ATF6-ODZ3-20-REOR 20 (40 μL) 200 μL
ATF6-ODZ3-20-REGO 20 (40 μL) 200 μL
ATF6-ODZ3-20-REGR 20 (40 μL) 200 μL
ATF6-ODZ3-20-REAQ 20 (40 μL) 200 μL
ATF6-ODZ3-20-ORRE 20 (40 μL) 200 μL
ATF6-ODZ3-20-OROR 20 (40 μL) 200 μL
ATF6-ODZ3-20-ORGO 20 (40 μL) 200 μL
ATF6-ODZ3-20-ORAQ 20 (40 μL) 200 μL
ATF6-ODZ3-20-GORE 20 (40 μL) 200 μL
ATF6-ODZ3-20-GOOR 20 (40 μL) 200 μL
ATF6-ODZ3-20-GOGO 20 (40 μL) 200 μL
ATF6-ODZ3-20-GOGR 20 (40 μL) 200 μL
ATF6-ODZ3-20-GOAQ 20 (40 μL) 200 μL
ATF6-ODZ3-20-GRRE 20 (40 μL) 200 μL
ATF6-ODZ3-20-GROR 20 (40 μL) 200 μL
ATF6-ODZ3-20-GRGO 20 (40 μL) 200 μL
ATF6-ODZ3-20-GRGR 20 (40 μL) 200 μL
ATF6-ODZ3-20-GRAQ 20 (40 μL) 200 μL
ATF6-ODZ3-20-AQRE 20 (40 μL) 200 μL
ATF6-ODZ3-20-AQOR 20 (40 μL) 200 μL
ATF6-ODZ3-20-AQGO 20 (40 μL) 200 μL
ATF6-ODZ3-20-AQGR 20 (40 μL) 200 μL
ATF6-ODZ3-20-AQAQ 20 (40 μL) 200 μL

ATF6 Gene Summary

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]

Gene Name: Activating Transcription Factor 6

Chromosome: CHR1: 161736033 -161933860

Locus: 1q23.3

Gene Diseases

The ATF6 ODZ3 Fusion has been associated with the following diseases:

Disease Name
Sarcoma
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.