ATG4B-DTYMK Fusion FISH Probe
The ATG4B-DTYMK Fusion FISH Probe is used to confirm a fusion of the ATG4B and DTYMK genes. The fusion of the ATG4B and DTYMK genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATG4B-DTYMK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-RERE | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-REOR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-REGO | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-REGR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-REAQ | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-ORRE | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-OROR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-ORGO | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GORE | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GOOR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GOGO | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GOGR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GRRE | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GROR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GRGO | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GRGR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-AQRE | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-AQOR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-AQGO | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-AQGR | 20 (40 μL) | 200 μL |
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| ATG4B-DTYMK-20-AQAQ | 20 (40 μL) | 200 μL |
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DTYMK Gene Summary
The Deoxythymidylate Kinase (DTYMK) gene is located on chr2 :242615156-242626383 at 2q37.3.
Gene Name: Deoxythymidylate Kinase
Chromosome: CHR2: 242615156 -242626383
Locus: 2q37.3
ATG4B Gene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Autophagy Related 4B Cysteine Peptidase
Chromosome: CHR2: 242577026 -242613271
Locus: 2q37.3
Gene Diseases
The ATG4B DTYMK Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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