ATP11B-TFRC Fusion FISH Probe
The ATP11B-TFRC Fusion FISH Probe is used to confirm a fusion of the ATP11B and TFRC genes. The fusion of the ATP11B and TFRC genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP11B-TFRC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-RERE | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-REOR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-REGO | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-REGR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-OROR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GORE | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GROR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP11B-TFRC-20-AQAQ | 20 (40 μL) | 200 μL |
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TFRC Gene Summary
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Gene Name: Transferrin Receptor
Chromosome: CHR3: 195776154 -195809032
Locus: 3q29
ATP11B Gene Summary
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Gene Name: ATPase Phospholipid Transporting 11B (putative)
Chromosome: CHR3: 182511290 -182639421
Locus: 3q26.33
Gene Diseases
The ATP11B TFRC Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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