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ATP2B1-RBM19 Fusion FISH Probe

The ATP2B1-RBM19 Fusion FISH Probe is used to confirm a fusion of the ATP2B1 and RBM19 genes. The fusion of the ATP2B1 and RBM19 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ATP2B1-RBM19-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ATP2B1-RBM19-20-RERE 20 (40 μL) 200 μL
ATP2B1-RBM19-20-REOR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-REGO 20 (40 μL) 200 μL
ATP2B1-RBM19-20-REGR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-REAQ 20 (40 μL) 200 μL
ATP2B1-RBM19-20-ORRE 20 (40 μL) 200 μL
ATP2B1-RBM19-20-OROR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-ORGO 20 (40 μL) 200 μL
ATP2B1-RBM19-20-ORAQ 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GORE 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GOOR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GOGO 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GOGR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GOAQ 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GRRE 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GROR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GRGO 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GRGR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-GRAQ 20 (40 μL) 200 μL
ATP2B1-RBM19-20-AQRE 20 (40 μL) 200 μL
ATP2B1-RBM19-20-AQOR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-AQGO 20 (40 μL) 200 μL
ATP2B1-RBM19-20-AQGR 20 (40 μL) 200 μL
ATP2B1-RBM19-20-AQAQ 20 (40 μL) 200 μL

ATP2B1 Gene Summary

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Gene Name: ATPase Plasma Membrane Ca2+ Transporting 1

Chromosome: CHR12: 89981825 -90049844

Locus: 12q21.33

RBM19 Gene Summary

This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

Gene Name: RNA Binding Motif Protein 19

Chromosome: CHR12: 114254542 -114404176

Locus: 12q24.13-q24.21

Gene Diseases

The ATP2B1 RBM19 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.