ATP5A1-HAUS1 Fusion FISH Probe
The ATP5A1-HAUS1 Fusion FISH Probe is used to confirm a fusion of the ATP5A1 and HAUS1 genes. The fusion of the ATP5A1 and HAUS1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP5A1-HAUS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-RERE | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-REOR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-REGO | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-REGR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-OROR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GORE | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GROR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP5A1-HAUS1-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5A1 Gene Summary
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Alpha Subunit 1, Cardiac Muscle
Chromosome: CHR18: 43664109 -43684199
Locus: 18q21.1
HAUS1 Gene Summary
HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Gene Name: HAUS Augmin Like Complex Subunit 1
Chromosome: CHR18: 43684297 -43708299
Locus: 18q21.1
Gene Diseases
The ATP5A1 HAUS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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