ATP6AP1-ARFGEF2 Fusion FISH Probe
The ATP6AP1-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the ATP6AP1 and ARFGEF2 genes. The fusion of the ATP6AP1 and ARFGEF2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP6AP1-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP6AP1 Gene Summary
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
Gene Name: ATPase H+ Transporting Accessory Protein 1
Chromosome: CHRX: 153656977 -153664862
Locus: Xq28
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The ATP6AP1 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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