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ATP6AP1-CCT5 Fusion FISH Probe

The ATP6AP1-CCT5 Fusion FISH Probe is used to confirm a fusion of the ATP6AP1 and CCT5 genes. The fusion of the ATP6AP1 and CCT5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ATP6AP1-CCT5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-RERE 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-REOR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-REGO 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-REGR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-REAQ 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-ORRE 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-OROR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-ORGO 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-ORAQ 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GORE 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GOOR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GOGO 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GOGR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GOAQ 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GRRE 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GROR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GRGO 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GRGR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-GRAQ 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-AQRE 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-AQOR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-AQGO 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-AQGR 20 (40 μL) 200 μL
ATP6AP1-CCT5-20-AQAQ 20 (40 μL) 200 μL

ATP6AP1 Gene Summary

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]

Gene Name: ATPase H+ Transporting Accessory Protein 1

Chromosome: CHRX: 153656977 -153664862

Locus: Xq28

CCT5 Gene Summary

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]

Gene Name: Chaperonin Containing TCP1 Subunit 5

Chromosome: CHR5: 10250281 -10266501

Locus: 5p15.2

Gene Diseases

The ATP6AP1 CCT5 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.