ATP6V1D-ZFYVE26 Fusion FISH Probe
The ATP6V1D-ZFYVE26 Fusion FISH Probe is used to confirm a fusion of the ATP6V1D and ZFYVE26 genes. The fusion of the ATP6V1D and ZFYVE26 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP6V1D-ZFYVE26-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-RERE | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-REOR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-REGO | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-REGR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-OROR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GORE | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GROR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP6V1D-ZFYVE26-20-AQAQ | 20 (40 μL) | 200 μL |
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ZFYVE26 Gene Summary
This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. [provided by RefSeq, Oct 2008]
Gene Name: Zinc Finger FYVE-type Containing 26
Chromosome: CHR14: 68213236 -68283306
Locus: 14q24.1
ATP6V1D Gene Summary
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008]
Gene Name: ATPase H+ Transporting V1 Subunit D
Chromosome: CHR14: 67804580 -67826720
Locus: 14q23.3
Gene Diseases
The ATP6V1D ZFYVE26 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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