ATP7A-PTPRR Fusion FISH Probe
The ATP7A-PTPRR Fusion FISH Probe is used to confirm a fusion of the ATP7A and PTPRR genes. The fusion of the ATP7A and PTPRR genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP7A-PTPRR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-RERE | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-REOR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-REGO | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-REGR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-OROR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GORE | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GROR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP7A-PTPRR-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP7A Gene Summary
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013]
Gene Name: ATPase Copper Transporting Alpha
Chromosome: CHRX: 77166193 -77305892
Locus: Xq21.1
PTPRR Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type R
Chromosome: CHR12: 71031852 -71314584
Locus: 12q15
Gene Diseases
The ATP7A PTPRR Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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